Benzquinamide hydrochloride
CAS No. 113-69-9
Benzquinamide hydrochloride ( 3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride )
Catalog No. M28949 CAS No. 113-69-9
Benzquinamide hydrochloride is an antiemetic agent and increases intra-arterial pressure due to the increased peripheral vascular resistance.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 231 | Get Quote |
|
10MG | 347 | Get Quote |
|
25MG | 582 | Get Quote |
|
50MG | 830 | Get Quote |
|
100MG | 1125 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameBenzquinamide hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionBenzquinamide hydrochloride is an antiemetic agent and increases intra-arterial pressure due to the increased peripheral vascular resistance.
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DescriptionBenzquinamide hydrochloride is an antiemetic agent and increases intra-arterial pressure due to the increased peripheral vascular resistance.(In Vivo):Benzquinamide (0.5 to 5 mg/kg; i.v.) caused tachycardia, elevated blood norepinephrine levels, frequent ventricular arrhythmias, and brief hypotension. Ganglionic blockade by hexamethonium prior to administration of benzquinamide prevented the tachycardia and alterations in norepinephrine levels but prolonged the period of hypotension. In isolated mesenteric arterial preparations, benzquinamide interfered with the contractile force generated by potassium chloride, norepinephrine, and prostaglandin F2 alpha.
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Synonyms3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride
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PathwayOthers
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TargetOther Targets
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RecptorTLR7
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Research Area——
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Indication——
Chemical Information
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CAS Number113-69-9
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Formula Weight443.0
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Molecular FormulaC22H35ClN2O5
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.CCN(CC)C(=O)C1CN2CCC3=CC(OC)=C(OC)C=C3C2CC1OC(C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nakamura T, et al. Synthesis and evaluation of 8-oxoadenine derivatives as potent Toll-like receptor 7 agonists with high water solubility. Bioorg Med Chem Lett. 2013 Feb 1;23(3):669-72.
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